Give notice immediately and give them 3 weeks. If they want to ef around with your vacation, you can say that it's take it or leave it for you.Give notice before I go on PTO, so 1 of those 2 weeks' notice is vacation. Give notice while I am on PTO. Can you use vacation time for 2 weeks' notice? Managers may be able to deny PTO requests from employees who resign with a 2-week notice letter. You can quit with zero notice, barring any contractual obligations. The "usual and customary" period is, of course, two weeks. The short answer is 'no'though two weeks may be necessary if you signed an employment agreement. Providing a twoweek notice is a common courtesy when resigning from a job.