Sample 2: Acceptance of Resignation with Immediate Effect. A simple and straightforward resignation means stating directly what you want to do — which is resign.Don't forget to add the position you're resigning from. Be direct and to the point and, in the first sentence, acknowledge the receipt of their letter of resignation and formally accept it. Give a clear reason for leaving, but there is no need to overexplain. Simply write that you are submitting your resignation effective xx date because you will be pursing other career opportunities.