How to write a resignation letter that's effective immediately? Learn how to write a resignation letter due to family reasons with our stepbystep guide and sample letters.This letter includes details such as your last day of employment, transition steps, words of gratitude and, optionally, your reasons for leaving. Dear Mr. Clark, I am writing to inform you that I am resigning from my position at Innovate Tech Labs, effective immediately. It's best to tell your boss that you're moving on to the next step in your career "facetoface or over video call," with at least two weeks' notice. Learn how to write an immediate resignation letter with our comprehensive guide, including tips, examples, and a customizable template. Your resignation letter should be to the point, concise, and clear. I would like to submit my notice effective immediately, making my last day . (For example, "I regret to inform you that I will be resigning from my position, effective immediately. This resignation letter is only for an employee who is resigning from a particular position, not the company itself.