Permits are available for various commercial properties. Explore the regulations and rules in each section below.This page is designed to provide small business owners and entrepreneurs with information they need to start or grow their business. The first, and most important step to consider, before you purchase or sign a lease, is to find out what types of businesses are allowed at the property. HOME-BASED BUSINESSES - Contact the Bexar Appraisal District Office at (210) 224-8511 for more information on reporting your business personal property. Discover how to launch your business in San Antonio with out all-inclusive guide. Find out how to navigate registration, taxes, licenses, and more. Well in San Antonio at least there is no Zoning code against running a home business. In general, sole proprietorships and partnerships need to register and file the business name (DBA or assumed name) with their local county clerk's office. A Certificate of Occupancy is required for all businesses in the City of San Antonio.