Patent foramen ovale closure can help reduce risk of another ischemic stroke. Learn more about a minimally-invasive treatment option.A patent foramen ovale doesn't need treatment unless it has caused a problem like a stroke or a TIA. The Amplatzer™ Talisman™ PFO Occluder is a device that can be placed in your heart to close the PFO through a minimally invasive, catheter-based technique. A PFO closure is a procedure that can help lower the risk of a stroke for some people. This efficient approach may be advantageous in optimizing workflow and minimizing hospital occupancy. This document addresses the transcatheter closure of patent foramen ovale and transcatheter or open left atrial appendage (LAA) closure. If you have a PFO and low blood oxygen levels or an unexplained stroke, you may need a procedure to close the hole. The presence of a patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions.