Attempt to Distribute a Controlled Substance (21 U.S.C. Sec. 846) is a federal crime that involves the attempted sale, transfer, exchange, or distribution of any controlled substance. A controlled substance is a drug or chemical that is regulated by the government due to its potential for abuse or addiction. Examples of controlled substances include cocaine, heroin, methamphetamine, and marijuana. Attempt to Possess with Intent to Manufacture or Distribute a Controlled Substance (21 U.S.C. Sec. 846) is a federal crime that involves the attempted acquisition, possession, or control of any controlled substance for the purpose of manufacturing or distributing it. This crime is typically charged when a person is found with a large quantity of a controlled substance, or with drug manufacturing materials and equipment. Manufacture of a Controlled Substance (21 U.S.C. Sec. 846) is a federal crime that involves the actual production or creation of a controlled substance. Examples of manufacturing a controlled substance include cooking, blending, or otherwise combining two or more drugs to create a new drug. Possession of a Controlled Substance (21 U.S.C. Sec. 846) is a federal crime that involves the actual possession of a controlled substance. This crime is typically charged when a person is found with a small amount of a controlled substance in their possession, such as a drug user who possesses a small amount of heroin.