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Plague bacteria are most often transmitted by the bite of an infected flea. During plague epizootics, many rodents die, causing hungry fleas to seek other sources of blood. People and animals that visit places where rodents have recently died from plague are at risk of being infected from flea bites.

Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45.

The plague is thought to have originated in Asia over 2,000 years ago and was likely spread by trading ships, though recent research has indicated the pathogen responsible for the Black Death may have existed in Europe as early as 3000 B.C.

Antibiotics such as , , , or are used to treat plague. Oxygen, intravenous fluids, and respiratory support are usually also needed. People with pneumonic plague must be kept away from other patients and isolation procedures will be followed in the hospital.

Infection control Human and animal plague are reportable diseases in the United States. Local and state health departments, state wildlife department, state agriculture departments should immediately be notified of any suspect cases.

Plague is caused by tiny living things called bacteria. It is mostly a disease of rats. Fleas that bite infected rats pick up the plague bacteria. They then spread it to other rats or to people through bites.

Diagnosis is made by taking samples from the patient, especially blood or part of a swollen lymph gland, and submitting them for laboratory testing. Once plague has been identified as a possible cause of the illness, appropriate treatment should begin immediately.

General Goal: To know the cause of this disease, the most common modes of transmission, the major manifestations, and the major complications of this disease. Specific Educational Objectives: The student should be able to: 1.

Plague bacteria are most often transmitted by the bite of an infected flea. During plague epizootics, many rodents die, causing hungry fleas to seek other sources of blood. People and animals that visit places where rodents have recently died from plague are at risk of being infected from flea bites.

Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45.

Laboratory Testing Lymph node aspirate: An affected bubo typically contains numerous organisms that can be evaluated microscopically and by culture. Blood cultures: Routine blood cultures are a sensitive means of detecting plague.

The plague is thought to have originated in Asia over 2,000 years ago and was likely spread by trading ships, though recent research has indicated the pathogen responsible for the Black Death may have existed in Europe as early as 3000 B.C.

Plague is a disease that affects humans and other mammals. It is caused by the bacterium, Yersinia pestis. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague.

RDTs are therefore useful diagnostic tools for use at the community level and in low‐resource settings. In the case of plague, the RDT detects the F1 capsular antigen of Y pestis (F1RDT), which is present in large amounts in buboes, blood, and sputum from patients infected with plague.

Antibiotics such as , , , or are used to treat plague. Oxygen, intravenous fluids, and respiratory support are usually also needed. People with pneumonic plague must be kept away from other patients and isolation procedures will be followed in the hospital.

Infection control Human and animal plague are reportable diseases in the United States. Local and state health departments, state wildlife department, state agriculture departments should immediately be notified of any suspect cases.

Plague is a disease caused by a kind of bacteria. In nature, the disease is spread from rodents to humans by the bite of a flea. During the fourteenth century, this illness spread across the world in three large waves, killing one-third to one-half of the population in places where outbreaks occurred.

Plague is caused by tiny living things called bacteria. It is mostly a disease of rats. Fleas that bite infected rats pick up the plague bacteria. They then spread it to other rats or to people through bites.

Diagnosis is made by taking samples from the patient, especially blood or part of a swollen lymph gland, and submitting them for laboratory testing. Once plague has been identified as a possible cause of the illness, appropriate treatment should begin immediately.

General Goal: To know the cause of this disease, the most common modes of transmission, the major manifestations, and the major complications of this disease. Specific Educational Objectives: The student should be able to: 1.

Laboratory Testing Lymph node aspirate: An affected bubo typically contains numerous organisms that can be evaluated microscopically and by culture. Blood cultures: Routine blood cultures are a sensitive means of detecting plague.

Plague is a disease that affects humans and other mammals. It is caused by the bacterium, Yersinia pestis. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague.

RDTs are therefore useful diagnostic tools for use at the community level and in low‐resource settings. In the case of plague, the RDT detects the F1 capsular antigen of Y pestis (F1RDT), which is present in large amounts in buboes, blood, and sputum from patients infected with plague.

Plague is a disease caused by a kind of bacteria. In nature, the disease is spread from rodents to humans by the bite of a flea. During the fourteenth century, this illness spread across the world in three large waves, killing one-third to one-half of the population in places where outbreaks occurred.