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TPN is administered into a vein, generally through a PICC (peripherally inserted central catheter) line, but can also be administered through a central line or port-a-cath. Patients may be on TPN for many weeks or months until their issues resolve.

Parenteral nutrition is administered from a bag containing the nutrients you need through tubing attached to a needle or catheter. With TPN, your healthcare provider places the catheter in a large vein, called the superior vena cava, that goes to your heart.

Because TPN solutions are concentrated and can cause thrombosis of peripheral veins, a central venous catheter is usually required.

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TPN requires special IV tubing with a filter. Generally, new TPN tubing is required every 24 hours to prevent catheter-related bacteremia.

Overview. Parenteral nutrition, often called total parenteral nutrition, is the medical term for infusing a specialized form of food through a vein (intravenously).

TPN is prepared by a pharmacy, where the calories are calculated using a formula, and is usually mixed for a 24-hour continuous infusion to prevent vascular trauma and metabolic instability (North York Hospital, 2013).

TPN delivers a mixture of fluid, electrolytes, sugars, amino acids (protein), vitamins, minerals, and often lipids (fats) into an infant's vein. TPN can be lifesaving for very small or very sick babies.

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