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Mice and rats make up approximately 95% of all laboratory animals, with mice the most commonly used animal in biomedical research.

Experimental models of disease are used to investigate processes thought to be involved in human diseases, and to evaluate and select drug candidates that affect these processes to support their progression into clinical trials.

A disease model is an animal or cells displaying all or some of the pathological processes that are observed in the actual human or animal disease. Studying disease models aids understanding of how the disease develops and testing potential treatment approaches.

Experimental model (or animal disease model) Animals that are employed to model the development and progression of diseases, and to test new treatments before they are given to humans, are used in experimental modelling.

​Animal Model Animal models (e.g., mice, rats, zebrafish and others) are sufficiently like humans in their anatomy, physiology or response to a pathogen that researchers can extrapolate the results of animal model studies to better understand human physiology and disease.

The disease model holds that the 'loss of control' experienced by 'addicts' or users in relation to drugs is the manifestation of an underlying disease state. The disease model has two relatively distinct strands: Enlightenment model. Medical disease model.

To understand what causes a disease, scientists often create a disease model – a biological system in the lab that mirrors a disease or shows some of the same disease processes.