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When applied to the skin, it spreads into the oil glands and starts working within minutes. Parastar Plus features a waterproof formula and gives your dog 30 days of lasting protection. Features easy to use, individual dose applicators.

Parastar Plus contains one of the same active ingredients, fipronil, as Frontline. So there's no change in that department. But… Parastar Plus combines fipronil with cyphenothrin, which kills ticks within 1 hour.

Parastar is a topical flea and tick preventative that contains fipronil, an insecticide. It kills fleas, ticks, chewing lice and helps control the mites that cause sarcoptic mange. It kills tick species that may transmit Lyme disease including dog ticks, American dog ticks, and lone star ticks.

Parastar Plusfor Dogs contains fipronil and cyphenothrin toeffectively start killing ticks and fleas in as little as 5 minutes. Kills ticks, including thosethatmay transmit Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, babesiosis, anaplasmosis and hepatozoonosis.

Fipronil (brand names: Frontline®, Barricade®, Easyspot®, Effipro®, Sentry Fiproguard®, Parastar®, PetArmor®, Pronyl OTC®, Spectra Sure®, and many others) is a topical medication used to treat fleas, ticks, and chewing lice infestations in dogs and cats.