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Breakpoint assembly To determine precise breakpoints use a third party tool e.g. TIGRA- SV velvet or a catalog of known breakpoints e.g. 1000 Genomes Genome STRiP generates calls with approximate coordinates typically 10- 20 bp resolu on Target site To u lize breakpoint- spanning reads in genotyping you need exact breakpoint coordinates. 0 -filterName DUPLICATE filter GSDUPLICATESCORE NA GSDUPLICATESCORE .

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