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ft = Q = A √D(2C с Cs) Cs t (7) where Q is the amount of drug released in time t per unit area A, C is the drug initial concentration, Cs is the drug solubility in the matrix media and D is the diffusivity of the drug molecules (diffusion coeffi- cient) in the matrix substance.

A cumulative% drug released vs. square root of time graph, denotes Higuchi model and the equation is, Q = K t1/2, where K is the constant expresses the design variables of the system and t is the time (in h). The equation signifies the drug release rate is inversely depends on the square root of time (Higuchi, 1963).

How is the index calculated? The index is calculated by dividing the column % of the crossover cell by the column % of the total cell for the relevant datapoint, and then multiplying by 100. Returning to the example above, we can calculate the index like so: (12.7/9.5)*100=133.7.

Sometimes an index has capping requirements which set the target weights for the index securities. An additional weight factor (AWF) is used to make market value adjustments to the index securities in order to satisfy the capping rules.

ft = Q = A √D(2C с Cs) Cs t (7) where Q is the amount of drug released in time t per unit area A, C is the drug initial concentration, Cs is the drug solubility in the matrix media and D is the diffusivity of the drug molecules (diffusion coeffi- cient) in the matrix substance.

A cumulative% drug released vs. square root of time graph, denotes Higuchi model and the equation is, Q = K t1/2, where K is the constant expresses the design variables of the system and t is the time (in h). The equation signifies the drug release rate is inversely depends on the square root of time (Higuchi, 1963).

How is the index calculated? The index is calculated by dividing the column % of the crossover cell by the column % of the total cell for the relevant datapoint, and then multiplying by 100. Returning to the example above, we can calculate the index like so: (12.7/9.5)*100=133.7.

Sometimes an index has capping requirements which set the target weights for the index securities. An additional weight factor (AWF) is used to make market value adjustments to the index securities in order to satisfy the capping rules.