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For WDSD 2023, we call for people and organisations around the world to be With Us Not For Us. People with disabilities have the right to be treated fairly and have the same opportunities as everyone else, working With others to improve their lives.

Although women older than 35 years of age make up a small portion of all births6 in the United States each year, about nearly one-half of babies with Down syndrome are born to women in this age group.

Results: We estimate that the number of people with DS living in the United States has grown from 49,923 in 1950 to 206,366 in 2010, which includes 138,019 non-Hispanic whites, 27,141 non-Hispanic blacks, 32,933 Hispanics, 6,747 Asians/Pacific Islanders, and 1,527 American Indians/American Natives.

In 2013, the theme of Wearing Odd Socks was initiated to raise awareness. Over time it has also been promoted as Lots of Socks. The idea was created because chromosomes are shaped “like socks” and people with Down syndrome have an extra chromosome.

Women who are 35 years or older when they become pregnant are more likely to have a pregnancy affected by Down syndrome than women who become pregnant at a younger age.3-5However, the majority of babies with Down syndrome are born to mothers less than 35 years old, because there are many more births among younger women ...

In a sample of 75 children with trisomy for chromosome 21, or Down syndrome, there were 42 males and 33 females. The sex ratio was 1.30 which is statistically not significant (p greater than 0.05).

Inheritance. Most cases of Down syndrome are not inherited. When the condition is caused by trisomy 21, the chromosomal abnormality occurs as a random event during the formation of reproductive cells in a parent. The abnormality usually occurs in egg cells, but it occasionally occurs in sperm cells.

However, with appropriate medical care most children and adults with Down syndrome can lead healthy lives. The average life expectancy of individuals with Down syndrome is 60 years, with many living into their sixties and seventies.