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Get to participate this year? Did you know that you can participate and raise much needed funds for research without attending an actual TeamWalk? The Walker by Proxy program is a way that you can help raise money from your home. Please log onto www.sp-foundation.org for details on how you can help. The best way to get donations is by asking family and friends for a personal donation. If that is uncomfortable for you, you can send a letter or email. The SPF website has several examples of lette.

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There are no treatments to prevent, slow, or reverse HSP. Treatments such as muscle relaxers can sometimes relieve spasticity. Regular physical therapy is important for muscle strength and to keep range of motion.

The prevalence of spastic paraplegia type 4 is estimated to be 2 to 6 in 100,000 people worldwide. This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.

Some children with AP-4-HSP have reached their early 20s, but long-term life expectancy for this condition is still unclear, as it was only first recognized in 2011. However, many children with hereditary spastic paraplegias in general have a normal life expectancy.

Depending on the HSP gene involved, symptoms may begin in childhood or adulthood. There are no treatments to prevent, slow, or reverse HSP. Treatments such as muscle relaxers can sometimes relieve spasticity. Regular physical therapy is important for muscle strength and to keep range of motion.

For SPG4, patients were calculated to live, on average, 24.7 years without symptoms, followed by 56.1 years with symptoms. For SPG11, SPG7, and SPG15, the same approach was followed, resulting in average years lived of 13.0, 36.8, and 14.6 without symptoms, and 60.6, 44.0, and 59.0 with symptoms, respectively (Fig.

The primary symptom of HSP is difficulty walking due to spasticity and weakness in the legs. Both legs are affected, usually to a relatively similar degree. The term “paraplegia” means severe weakness in both legs (similar to “paralysis”).

Most people with pure hereditary spastic paraplegia will have inherited a faulty gene from one of their parents. People with the complicated form of the condition will have usually inherited a faulty gene from both parents. The gene abnormality causes the long nerves in the spine to deteriorate.

Symptoms of HSP may begin at any age, from infancy to older than 60 years. If symptoms begin during the teenage years or later, then spastic gait disturbance usually progresses insidiously over many years. Canes, walkers, and wheelchairs may eventually be required.

Spastic paralysis can occur when the upper motor neurons become damaged, resulting in a loss of voluntary control over the affected muscles. With spastic paralysis, the signals that tell the muscles to contract or relax are imbalanced. The muscles respond to this by becoming tight and hard.

Hereditary spastic paraplegia due to SPG4 gene mutation is the single most common form of autosomal dominant HSP, and possibly the single most common form of any type of HSP.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232