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Of failed syntheses using a minimal amount of sample (Williams 1998). MALDI is particularly advantageous in this respect, allowing the analysis of product not detected by traditional PAGE (Williams 1998). Figure 1 shows the linear MALDI TOFMS of the oligonucleotide mix. Intensity 6801.8 Materials and Methods The sample preparation method used a combination of O Donnell (1997) and Langley (1999). All samples were diluted to give a final concentration of approximately 6 pmole/ l. Unpur.

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