A PFO closure is a surgical procedure to close the hole that should have sealed on its own after birth. In this procedure, the provider inserts a thin, flexible tube called a catheter into a blood vessel in the groin area.The surgeons at our adult congenital heart center perform patent foramen ovale closures and actively research innovative techniques to treat the condition. Many people don't need treatment unless they're at risk of stroke or blood clots. Patent foramen ovale closure is a procedure to close a hole in the heart. We use minimally invasive approaches to treat PFO without open-chest surgery. Patent foramen transcatheter repair is a procedure to fix this hole in the heart. Normally, the atrial septum separates the right and left atria. Patent foramen ovale (PFO) is a hole between the left and right atria (upper chambers) of the heart. This hole exists in everyone before birth.