A PFO closure uses a medical device to close an opening between your heart's two upper chambers. You only need this opening as a fetus.A PFO closure fills an opening between your heart's two upper chambers. However, percutaneous closure is now more commonplace. It's open when babies are in the womb and usually closes within the first year of life. Creating a small incision in the groin, a catheter is guided to the heart and the closure device is carefully placed to close the hole from both sides. Most people with a patent foramen ovale don't need treatment. A PFO is a type of hole in the heart that occurs in infancy. If you have a PFO and low blood oxygen levels or an unexplained stroke, you may need a procedure to close the hole. A foramen ovale is a small hole in the heart that naturally exists in babies who are still in the womb.