A surgical closure of the PFO is done for patients < 60 yr with unclear cause for stroke despite extensive workup to reduce recurrence of another stroke. PFO closure is an outpatient, catheter-based procedure that lasts between one and two hours.The foramen ovale is a hole in the wall between the left and right atria of every human fetus. This hole allows blood to bypass the fetal lungs. Patent foramen ovale (PFO); Prosthetic valve paravalvular leaks; Ventricular septal defects (VSD). Treatment options in Fort Worth. Patients who do need treatment may take medicines or have a percutaneous coronary intervention to close the PFO. In more serious cases, surgery may be needed. Dr. Pool has done many ASD closures with a minimally-invasive approach. Patients are usually in the hospital 4-5 days after a minimally-invasive closure of ASD.