In SW Florida, only Lee Health's specially trained physicians perform PFO repair. Call 239-445-4775 for more information.PFO is a flaplike hole in the interatrial septum that can allow blood to go from the right to left chambers and could be a cause for stroke. In this procedure, the provider inserts a thin, flexible tube called a catheter into a blood vessel in the groin area. A patent foramen ovale occurs when a hole that is always present in a newborn's heart fails to close as it should once the lungs begin to function after birth. A PFO closure uses a medical device to close an opening between your heart's two upper chambers. You only need this opening as a fetus. Your Florida Heart, Vein and Vascular Institute provider performs a minimally invasive catheter-based procedure to close the hole. Patent foramen ovale (PFO) is a hole between your heart's upper chambers. Patent foramen ovale (PFO) is a small hole between the upper right and left chambers (atria) of your heart.