In SW Florida, only Lee Health's specially trained physicians perform PFO repair. Call 239-445-4775 for more information.For children needing treatment for a PFO, we use cardiac catheterization to close the defect with a small device. Most people with a patent foramen ovale don't need treatment. If PFO is not causing any problems or symptoms, treatment is not required. Patent foramen ovale (PFO) is a hole between your heart's upper chambers. Learn more about the causes and complications of this condition in which a hole in the heart doesn't close the way it should after birth. A PFO closure uses a medical device to close an opening between your heart's two upper chambers. You only need this opening as a fetus. Clinical Study investigators and partici- pating organizations is provided in the.