Vanderbilt Heart Franklin, KY. 121 Memorial Drive. Assignee: FRANKLIN PRODUCTS, INC.Inventor: Howard Velasco. This page provides information on the types of patents and types of patent applications, and the examination process. Imaging description. Patent foramen ovale (PFO) is a congenital anatomical variant which is associated with strokes in young adults. To minimize recall bias, patients were asked to complete the questionnaire as soon as possible after stroke. Justia - Patents - Patents and Patent Application Resources. Franklin. 2. 9.0. 1.1. 32.7. Richland. 2. 23.5. There have been several studies evaluating secondary stroke prevention of patent foramen ovale closure since the previous guideline in 2014.