Patent foramen ovale (PFO) closure involves closing a small tunneled hole in the heart that has been linked to an increased risk of stroke. Our team of interventional cardiologists specializes in a minimally invasive PFO closure procedures.The foramen ovale is a hole in the wall between the left and right atria of every human fetus. This hole allows blood to bypass the fetal lungs. Patent foramen ovale (PFO) is a hole between your heart's upper chambers. However, it may cause serious complications under certain circumstances. In this procedure, the provider inserts a thin, flexible tube called a catheter into a blood vessel in the groin area. Northwestern Medicine Neuroscience programs provide treatment for a full range of potential neurological concerns, including patent foramen ovale. Discusses patent foramen ovale, which is an opening in the septum of the heart between the upper right and left chambers. Covers diagnosis and treatment.