Treatments include medications and closure of the hole with a catheter or surgery. If you have a PFO and low blood oxygen levels or an unexplained stroke, you may need a procedure to close the hole.Implantation of an Occlutech Figulla PFO occluder in a patient with patent foramen ovale and history of embolic stroke. Cardiol J. 2008;0-382. Patent foramen ovale closure is a procedure to close a hole in the heart. We use minimally invasive approaches to treat PFO without open-chest surgery. Hemorrhagic strokes occur most often in patients with poorly controlled high blood pressure. An ischemic stroke occurs when a blockage develops in a blood. Planned intracardiac echocardiography).