How is Patent Foramen Ovale Treated? Most people with a patent foramen ovale don't need treatment.Our Adult Congenital Heart Center in New York City is a pioneer in the treatment of stroke-related patent foramen ovale. Call today 212-305-6936. PFO often has no symptoms. Many people don't need treatment unless they're at risk of stroke or blood clots. Patent foramen transcatheter repair is a procedure to fix this hole in the heart. Normally, the atrial septum separates the right and left atria. However, it may cause serious complications under certain circumstances.