A patent foramen ovale doesn't need treatment unless it has caused a problem like a stroke or a TIA. Most people with a patent foramen ovale don't need treatment.How is Patent Foramen Ovale Treated? Patent foramen ovale (PFO) is a hole between your heart's upper chambers. However, it may cause serious complications under certain circumstances. The healthcare provider inserts the catheter through a blood vessel in the groin and guides it to the PFO.