Move a special balloon on a catheter to the area of the hole. Inflate the balloon to measure the size of the hole.Premier Health offers a full range of heart and vascular care – preventive, diagnostic, nonsurgical, surgical, and rehab – across Southwest Ohio. Many people don't need treatment unless they're at risk of stroke or blood clots. Adena Regional Medical Center 272 Hospital Rd. Chillicothe, OH 45601 740 779 7500. The healthcare provider inserts the catheter through a blood vessel in the groin and guides it to the PFO. A PFO closure is a procedure that can help lower the risk of a stroke for some people. A patent foramen ovale (PFO) is a hole in the heart that didn't close the way it should after birth. What is the PFO closure procedure? Learn about patent foramen ovale (PFO), risk of PFO-associated stroke, and treatment options for PFO closure.