The team at Arizona Heart Arrhythmia Associates can diagnose your structural heart defect and provide treatments to keep your heart working as it should. The foramen ovale normally closes after birth.But sometimes it stays open. A patent foramen ovale (PFO) is a hole in the heart that didn't close the way it should after birth. A patent foramen ovale (PFO) is a hole in the heart that should have closed after birth. Learn more about the causes and complications of this condition in which a hole in the heart doesn't close the way it should after birth. The purpose of this study is to evaluate Patent Foramen Ovale (PFO) closure for migraine headache relief using the GORE® CARDIOFORM Septal Occluder. Patent foramen ovale closure is a procedure to close a hole in the heart. We use minimally invasive approaches to treat PFO without open-chest surgery. This occurs when there is a defect in the wall between the coronary sinus and the left atrium.