Most people with a patent foramen ovale don't need treatment. Patent foramen transcatheter repair is a procedure to fix this hole in the heart.Normally, the atrial septum separates the right and left atria. Patent foramen ovale (PFO) is a hole between the left and right atria (upper chambers) of the heart. This hole exists in everyone before birth. The foramen ovale is a hole in the wall between the left and right atria of every human fetus. This hole allows blood to bypass the fetal lungs. Patent foramen ovale (PFO) is a hole between your heart's upper chambers. A PFO closure is a procedure that can help lower the risk of a stroke for some people. A patent foramen ovale (PFO) is a hole in the heart that didn't close the way it should after birth.