The Fourth Amendment guards against unreasonable searches and seizures during multiple circumstances, including traffic stops. The Fourth Amendment requires the government to obtain a warrant based on probable cause to conduct a legal search and seizure.Debates over the scope of unreasonable searches and seizures sparked the American Revolution as we'll learn in a moment. The Fourth Amendment to the U.S. Constitution protects individuals from unreasonable searches and seizures. The Fourth Amendment protects against unreasonable searches and seizures. It requires a warrant, based on probable cause, for searches. Marijuana was discovered in the glove compartment. Searches and Seizures Pursuant to Warrant. Semayne's case was argued in 1604 and the court basically decided, as recorded by. That's why the Fourth Amendment protects "persons" from unreasonable searches and seizures.