Title VII prohibits employment discrimination based on race, color, religion, sex and national origin. As a threshold question, employers will need to decide whether to require employees to be vaccinated or instead to make vaccination voluntary.ADA Exemption: The employee has a disability which prevents them from receiving the COVID vaccination. OSHA will issue ETSs mandating employers with 100 or more employees require employees to either be vaccinated or submit to weekly testing. Contractors, among other U.S. employers. The hospital network moved to dismiss. Title VII of the Civil Rights Act of 1964 prohibits religious discrimination in the workplace. Sex," in violation of Title VII of the Civil Rights Act of 1964.