Treating one or more members of a specified group unfairly as compared with other people. A central problem is how to define discrimination, both in its most basic direct sense and in the most prominent variations.What does the noun discrimination mean? The practice of treating someone or a particular group in society less fairly than others. Please visit Trillium's Hurricane Helene page for information from NCDHHS, recovery efforts, and more. We Are Trillium Health Resources. Oxford, MD 2165 4 (410) 226-5527. American Chemical Society (ACS). Find definitions for over 300000 words from the most authoritative English dictionary. Continuously updated with new words and meanings.