Treating one or more members of a specified group unfairly as compared with other people. The meaning of DISCRIMINATION is prejudiced or prejudicial outlook, action, or treatment.How to use discrimination in a sentence. The practice of treating someone or a particular group in society less fairly than others. What does the noun discrimination mean? Discrimination is an action or practice that excludes, disadvantages, or merely differentiates between individuals or groups of individuals Discrimination means treating a person 'less favourably' than someone else, because of protected characteristics outlined in the Equality Act 2010. Strong diversity climates are also associated with reduced instances of interpersonal aggression and discrimination.