The meaning of DISCRIMINATION is prejudiced or prejudicial outlook, action, or treatment. How to use discrimination in a sentence.Discrimination is the unfair or prejudicial treatment of people and groups based on characteristics such as race, gender, age, or sexual orientation. Discrimination means, at a very basic level, the act of separating out singular things or groups of things. It can be both an adjective and a verb. Discrimination is unfair treatment of one particular person or group of people. Discrimination, the intended or accomplished differential treatment of persons or social groups for reasons of certain generalized traits. Discrimination is the process of making unfair or prejudicial distinctions between people based on the groups, classes, or other categories to which they belong Travis Education Center, unless otherwise posted. Bullying situations not only affect the student who is bullied or the students who are doing the bullying.