In this article, we discuss how to include a reason in your resignation letter and provide some samples to guide your writing. How to write a resignation letter that's effective immediately?Below are some ProTips and a sample resignation letter that you can edit based on the details of your own individual situation. Use an attractive header with your personal contact info, include the recipient's name, company and address, and include the date. These top samples of resignation letters for personal reasons can be used as helpful templates when you are looking to resign due to personal circumstances. Please accept this letter as a notice of my resignation. Example letters to resign for family or personal reasons.