Dear Bill: It is with great regret that I accept your resignation as Administrator of the Environmental Protection Agency. Learn how to write a response to a resignation letter and use our examples and template to help you write your own.Master the art of writing a resignation letter with our comprehensive guide, offering step-by-step instructions, tips, and templates. The letter should state that you regret the loss of the employee, but respect and understand their decision. To whom it may concern: Please accept this letter as my formal resignation as JOB TITLE for COMPANY to become effective as of DATE.