In this article, we will discuss how to write a resignation letter as a nurse and provide examples and tips. A nursing resignation letter serves as formal notice to your employer that you're leaving your position.It shows professionalism and courtesy. For example, "This letter is to formally give notice that I am resigning my position as a nurse practitioner at Jennings Hospital. I am writing to inform you of my resignation as a Registered Nurse at St. Joseph's Nursing Center. My last day of work will be January 19, 2022.