It's best to tell your boss that you're moving on to the next step in your career "facetoface or over video call," with at least two weeks' notice. How to write a resignation letter that's effective immediately?Here are examples of resignation letters for different levels and professions, each tailored to a specific personal reason. Learn how to write a resignation letter due to family reasons with our stepbystep guide and sample letters. A letter of resignation does not need a reason. This letter includes details such as your last day of employment, transition steps, words of gratitude and, optionally, your reasons for leaving. Your resignation letter should be to the point, concise, and clear.