Address line; Statement of resignation; Last day of work; Statement of gratitude; Next steps; Closing and signature. We've crafted two formats for your nursing resignation: a written letter and an email.A simple and straightforward resignation means stating directly what you want to do — which is resign. Don't forget to add the position you're resigning from. Be Concise and Clear: While expressing gratitude is important, keep the letter concise and to the point. Keep it short and simple. Format like a business letter. What is a resignation letter, and how do you write one? Here are sample letters and templates, as well as tips for how to resign gracefully. Nursing resignation letters are formal communications that must include specific information.