Learn how to draft your nursing resignation letter using our samples, tips and templates. I would like to formally submit my resignation notice effective _____.I regret to inform you that I am resigning from my position as "night shift RN for Nice Hospital". The complete guide to writing a nursing resignation letter with tips, examples, and templates. This letter is to officially notify you of my resignation, effective ____ (last date of employment). How do I resign from a nursing job? Your statement of intent to resign should include the title of your position with the company and the company's name. Our Resignation Letter Sample Templates are quick and easy-to-use. They each include formatting and content that sets you up for success. If possible, write the letter at least two weeks before resigning from your job.