In this article, we will discuss how to write a resignation letter as a nurse and provide examples and tips. I regret to inform you that I am resigning from my position as "night shift RN for Nice Hospital".A nursing resignation letter serves as formal notice to your employer that you're leaving your position. It shows professionalism and courtesy. The complete guide to writing a nursing resignation letter with tips, examples, and templates. How do I convey that I am grateful for my time on this floor, and at the same time be truthful about the flaws that have caused me to resign? In the body of the letter, immediately state your intention to resign and provide your reasoning, including only positive feelings towards your work experience. Dear Director Cruz,. By submitting a nurse resignation letter to the office, you begin the procedure of resignation. This letter is to officially notify you of my resignation, effective ____ (last date of employment).