Below are some ProTips and a sample resignation letter that you can edit based on the details of your own individual situation. To resign from your position, complete and submit a resignation letter to your supervisor at least two weeks, or as soon as possible, before your last day.Dear (Supervisor's Name),. What components should a resignation letter include? It's not going to hurt you op. It's a necessary formality. Keep it short and to the point. There's no reason to draw this letter out beyond a single page. Write that you are leaving for personal reasons. No further explanation is required.