Address line; Statement of resignation; Last day of work; Statement of gratitude; Next steps; Closing and signature. Use a proper greeting for your supervisor in the email.The complete guide to writing a nursing resignation letter with tips, examples, and templates. A simple and straightforward resignation means stating directly what you want to do — which is resign. Don't forget to add the position you're resigning from. Express Gratitude: Express gratitude to colleagues, supervisors, and the organization. Nursing resignation letters are formal communications that must include specific information. Use these tips to craft a professional letter. Offer to assist with the transition process, such as training a replacement or completing any outstanding tasks before your departure. In the body of the letter, state your intended retirement date (your last day) and your thoughts on a transition plan.