Pick the perfect wording and convey the message best suited for your situation. Simply write that you are submitting your resignation effective xx date because you will be pursing other career opportunities.If you want to keep it professional you should avoid the detailed laundry list. Be prepared for an emotional or difficult conversation. Clearly and calmly explain your reason for leaving, and present your resignation letter. Just state the position you're resigning from and the effective date. Be crystal clear that you're leaving the job. Want to know how to write a retirement letter of resignation? Get the insights you need and free retirement letter template to help guide the way. Professional resignation letter examples for different reasons.