It's time to quit the job, and you're not giving two weeks' notice. Here's how to politely write a resignation letter, effective immediately.Use a formal and polite tone, including appropriate salutations and signoffs, to convey professionalism and respect. How to write a resignation letter that's effective immediately? Check for a company policy regarding quitting do you need to give more than 2 weeks' notice? The best opening statement for a resignation letter is one that clearly states your intentions. To make a graceful exit, you'll want a resignation letter that clearly states your intention to leave, but also offers a word of thanks. Be specific in your reason for leaving in the resignation letter and do not verbally contradict your statements with your coworkers.