The complete guide to writing a nursing resignation letter with tips, examples, and templates. A nursing resignation letter serves as formal notice to your employer that you're leaving your position.It shows professionalism and courtesy. In this article, we will discuss how to write a resignation letter as a nurse and provide examples and tips. I am writing to inform you of my resignation as a Registered Nurse at St. Joseph's Nursing Center. My last day of work will be January 19, 2022. I regret to inform you that I am resigning from my position as "night shift RN for Nice Hospital". Dear manager, i am resigning my position as staff nurse effective three weeks from today (put the actual calendar date there). This decision aligns with my long-term career goals, and I am excited about the new challenges that await me. Check out our nurse resignation letter template selection for the very best in unique or custom, handmade pieces from our templates shops.