Resignation letters shoulf always be polite. They should have no negative or critical feedbacks.Resignation letter effective immediately due to toxic environment. Briefly describe your experience. You can describe any negative experiences you've had that you feel are necessary to include. When resigning due to a toxic work environment, maintain professionalism. Is your work environment toxic? Alcohol, Smoking, and Drug-free Workplace. All share in the responsibility of improving the quality of our work environment. By deciding to work here, you agree to follow our rules.