Learn how to draft your nursing resignation letter using our samples, tips and templates. Nursing resignation letters are formal communications that must include specific information.Use these tips to craft a professional letter. Leaving a nursing job can feel overwhelming. However, writing a nurse resignation letter can help ensure a smooth transition. The complete guide to writing a nursing resignation letter with tips, examples, and templates. Thank you for allowing me the opportunity of employment at your facility. A nurse resignation letter is needed to notify the management of planned resignation from work. By submitting a nurse resignation letter to the office, you begin the procedure of resignation. You want to give at least a two weeks' notice.