Discover how to craft a professional resignation letter due to illness. Want to quit your job due to health problems?Know how to write the perfect resignation letter due to health issues, with this guide and multiple samples. I am writing to inform you that I will be resigning from my current position, X at X, effective immediately. Please accept this letter as formal notice. To help you draft your resignation letter like the example above, here's a checklist of what to include: What to include in a resignation letter. Outline what you'd like to say - try to stay direct, positive and professional as possible. This letter is typically addressed to the board, chairperson, or relevant authority within the organization. 2) Write a resignation letter. Most states in the U.S., including Pennsylvania and New Jersey, are "atwill" employment states.