A nursing resignation letter serves as formal notice to your employer that you're leaving your position. It shows professionalism and courtesy.In this article, we will discuss how to write a resignation letter as a nurse and provide examples and tips. In the first part, briefly introduce the letter and state the nurse's resignation. Keep it brief, polite, and professional in word and appearance. This letter is to officially notify you of my resignation, effective ____ (last date of employment). In typical occupational areas, two weeks' notice is required. Learn how to write a letter of resignation to quit your job on good terms.