The complete guide to writing a nursing resignation letter with tips, examples, and templates. Learn how to draft your nursing resignation letter using our samples, tips and templates.How should I structure my resignation letter? Please accept this letter as formal notice of my resignation from the position of Registered Nurse at Starlight Medical Center, effective November 19, 2024. Clearly state your intention to resign along with any relevant details such as your last working day. imageSign. Nursing RN Resignation Letter Format ; Heading. Your Name; Your Position (Registered Nurse); Your Address (optional); Date ; Salutation.